What is Super Vidalista 80 Mg? Super Vidalista 80 Mg is a fixed-dose combination prescription oral tablet containing two clinically distinct active pharmaceutical ingredients — Tadalafil 20 mg, a PDE5 inhibitor for erectile dysfunction, and Dapoxetine 60 mg, a short-acting SSRI for premature ejaculation. The "80 mg" in the product name reflects the combined total strength of both active ingredients (20 mg 60 mg). It is an on-demand medication — taken 1–3 hours before planned sexual activity, not on a daily schedule. Manufactured by Centurion Laboratories, the same company behind the widely trusted standard Vidalista Tadalafil tablets, Super Vidalista brings the proven reliability of the Vidalista brand to men who need comprehensive dual-condition management from a single, convenient dose. How Does Super Vidalista 80 Mg Work? Super Vidalista 80 Mg works through two independent, complementary pharmacological mechanisms — one for each active ingredient: Tadalafil 20 Mg — PDE5 Inhibition for Erection Support Tadalafil belongs to the phosphodiesterase type 5 (PDE5) inhibitor class — the most clinically validated category of oral ED medication available. During sexual arousal, the body releases nitric oxide in penile tissue, which triggers production of cyclic GMP (cGMP) — the molecule responsible for relaxing blood vessel walls and enabling blood to fill the erectile chambers (corpus cavernosum). In men with ED, the PDE5 enzyme degrades cGMP too rapidly before a sufficient erection is established. Tadalafil selectively blocks PDE5, preserving cGMP concentrations and sustaining the vasodilation necessary for a firm erection. With its 17.5-hour half-life — the longest of any PDE5 inhibitor — a single 20 mg Tadalafil dose keeps the erectile response available for up to 36 hours. Crucially, sexual stimulation must always be present — Tadalafil amplifies the body's natural arousal response, it does not create erections spontaneously. Dapoxetine 60 Mg — SSRI Action for Ejaculatory Delay Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) specifically designed for on-demand use in premature ejaculation — unlike traditional SSRIs which require weeks of daily dosing to build up effect. Premature ejaculation is driven in part by low serotonin activity in the central ejaculatory control pathways of the brain. Dapoxetine blocks serotonin reuptake in synaptic clefts, rapidly elevating serotonin concentration and raising the ejaculatory threshold — allowing a man to experience greater control over when he ejaculates. Its short half-life (approximately 1.5 hours) makes it ideal for on-demand use: the pharmacological effect is active during the sexual encounter and clears the system quickly, minimising next-day SSRI side effects. Together, these two molecules address ED and PE at the vascular and neurological levels simultaneously. What is Super Vidalista 80 Mg Used For? Super Vidalista 80 Mg is clinically prescribed for: Concurrent Erectile Dysfunction and Premature Ejaculation: The primary indication — for men who experience both conditions simultaneously, where treating only one leaves the other unaddressed and sexual dissatisfaction persists Performance Anxiety-Driven Dual Dysfunction: Anxiety about erection loss frequently triggers or worsens PE. By restoring reliable erections, the anxiety driving premature ejaculation is also reduced — and Dapoxetine provides additional ejaculatory control during the transition Acquired PE in Men with ED: Men who develop PE as a secondary consequence of ED — where the urgency to ejaculate before erection loss creates a conditioned PE pattern — benefit most from this combination approach Men Seeking a Single-Tablet Solution: Rather than managing two separate medications with different timing windows, Super Vidalista delivers both active ingredients in one tablet, one dosing event, one administration protocol Men who need ejaculatory delay without concurrent ED support may find a topical solution more appropriate. Explore our full Climax Spray collection — nine formulations of Lidocaine and Benzocaine delay sprays offering targeted, on-demand ejaculatory control without any systemic medication. Super Vidalista 80 Mg Dosage — How to Take It Correctly Follow your physician's prescription precisely. General dosage guidelines: Dose: One tablet (Tadalafil 20 mg Dapoxetine 60 mg) per 24-hour period — never exceed this limit Timing: Take 1–3 hours before planned sexual activity — Dapoxetine requires 1–1.5 hours to reach peak concentration, while Tadalafil begins working within 30–60 minutes. The wider window allows both ingredients to be fully active simultaneously With or without food: Can be taken with or without food — however, a high-fat meal may delay Tadalafil absorption and should be avoided if prompt onset is desired Swallow whole: Do not crush, split, or chew the tablet — this alters the release profile of both active ingredients, particularly Dapoxetine Alcohol: Avoid entirely — alcohol amplifies Dapoxetine's blood pressure-lowering effect, compounds dizziness, and independently impairs erection quality and ejaculatory control Grapefruit: Avoid grapefruit and grapefruit juice — inhibits CYP3A4 metabolism of Tadalafil, raising drug blood levels unpredictably The 36-hour Tadalafil window means the erectile response is available for up to 36 hours post-dose — providing multiple opportunities without re-dosing. Dapoxetine's ejaculatory delay effect is active for the first 3–4 hours, covering the primary window of sexual activity. For men considering a daily Tadalafil approach for background erection support, Vidalista 5 Mg is the appropriate low-dose daily option — but note that daily Tadalafil cannot be combined with Dapoxetine on the same day. Side Effects of Super Vidalista 80 Mg Side effects of Super Vidalista 80 Mg reflect the combined profiles of both active ingredients: Common Side Effects (Mild and Temporary) Headache — most frequently reported; caused by systemic vasodilation from Tadalafil and serotonergic activity from Dapoxetine Nausea and dizziness — Dapoxetine's SSRI activity and combined blood-pressure-lowering effect; most pronounced on the first few uses Facial flushing and nasal congestion — from Tadalafil-related vasodilation Back pain and myalgia — characteristic Tadalafil side effect via PDE11 activity; typically appears 12–24 hours post-dose and resolves within 48 hours Insomnia or sleep disturbance — Dapoxetine's SSRI activity may disrupt sleep if taken late in the day Dry mouth and indigestion — mild GI effects from the Dapoxetine component Temporary blurred vision or colour tint — less common with Tadalafil than Sildenafil due to lower PDE6 affinity Serious Side Effects — Seek Immediate Medical Attention Priapism: A prolonged, painful erection exceeding 4 hours without stimulation — a urological emergency. Permanent erectile tissue damage results if untreated. Go to an emergency room immediately Severe hypotension: Dangerous blood pressure drop — especially if combined with nitrate medications (absolutely prohibited) or when alcohol has been consumed Syncope (fainting): Dapoxetine lowers blood pressure; combined with Tadalafil's vasodilatory effect and alcohol, fainting is possible — most common when standing up quickly Sudden vision or hearing loss: Rare but serious adverse events associated with Tadalafil — discontinue immediately and seek emergency evaluation Serotonin syndrome: Rare risk when Dapoxetine is combined with other serotonergic drugs (MAOIs, SSRIs, SNRIs, tramadol) — presents as agitation, rapid heart rate, high temperature, and muscle rigidity. A medical emergency Never combine Super Vidalista with nitrate medications, MAOIs, or other SSRIs/SNRIs. For responsible medication use guidance, read our Medicine Policy. Who Should Not Take Super Vidalista 80 Mg? Super Vidalista 80 Mg is contraindicated in the following groups: Men taking nitrate medications (nitroglycerin, isosorbide mononitrate/dinitrate, or recreational nitrate inhalants) — the Tadalafil-nitrate combination causes a potentially fatal blood pressure drop. Absolutely no exceptions Men taking MAOIs (monoamine oxidase inhibitors) or who have used them within the past 14 days — combining with Dapoxetine creates severe serotonin toxicity risk Men currently using other SSRIs, SNRIs, tricyclic antidepressants, or lithium — Dapoxetine combined with these agents raises serotonin syndrome risk Men with severe cardiovascular disease, recent heart attack or stroke (within 6 months), uncontrolled hypertension, or severe heart failure Men with significant liver impairment — both Tadalafil and Dapoxetine are hepatically metabolised; impaired liver function raises blood levels of both drugs dangerously Men with severe renal impairment Men under 18 or over 64 years of age — the combination has not been clinically validated in these age groups Known allergy to Tadalafil, Dapoxetine, or any excipient in the tablet Men who need Tadalafil only — without the Dapoxetine component — should explore the full Tadalafil collection which includes everything from daily low-dose Vidalista 2.5 Mg to the high-strength Vidalista 80 Mg Black. Men who prefer Sildenafil-based therapy can explore our Cenforce collection instead. Super Vidalista 80 Mg vs Other Vidalista Variants — Which is Right for You? Super Vidalista sits in a unique position within the Vidalista range — it is the only variant combining Tadalafil with Dapoxetine. Here is how it compares to key alternatives: Vidalista 20 Mg (Tadalafil only): Best for men with ED and normal ejaculatory control who need the standard 36-hour Tadalafil window without the SSRI component Vidalista 40 / 60 Mg (Tadalafil only): Stepped-up single-agent Tadalafil for men with moderate-to-severe ED who do not have concurrent PE Super Vidalista 80 Mg (Tadalafil 20 Dapoxetine 60): The definitive choice when both ED and PE are present simultaneously — delivers dual pharmacological action for both conditions in one tablet, one timing event Vidalista CT 20 Mg (Chewable Tadalafil): For men who prefer a no-water chewable Tadalafil format for faster onset without PE management. Explore our Vidalista CT 20 Mg product page Vidalista Professional 20 Mg (Sublingual): For men who need the fastest possible Tadalafil onset (15–20 minutes via sublingual absorption) without the Dapoxetine component. See Vidalista Professional 20 Mg Unsure which ED medication best suits your health profile and performance goals? Read our guide to the best pill for ED for a detailed, evidence-based comparison of all major oral ED treatments — including how Super Vidalista compares against Sildenafil, Vardenafil, and standalone Tadalafil options. Why Buy Super Vidalista 80 Mg from Ed Care Store? Ed Care Store is built on a clear mission: making genuine, pharmaceutical-grade ED and sexual health treatments accessible, affordable, and completely private for men across the US. When you order Super Vidalista 80 Mg from us, you receive: Authentic Centurion Laboratories product — verified sourcing with no counterfeits or substitutions Competitive pricing far below what equivalent dual-action treatments cost elsewhere Discreet plain packaging — zero identifying health-related markings on the outside of every order Fast, reliable US-wide delivery — see our Shipping Policy for delivery timelines and free shipping eligibility Secure checkout and multiple payment options 24/7 customer support — call, text, or email at any time for product guidance, dosing questions, or order assistance Full sexual health range — pair with complementary solutions like our blog on lasting longer in bed for comprehensive performance support beyond medication alone Frequently Asked Questions (FAQs) How is Super Vidalista 80 Mg different from regular Vidalista? Regular Vidalista tablets (20 mg, 40 mg, 60 mg, 80 mg Black) contain Tadalafil only and treat erectile dysfunction exclusively. Super Vidalista 80 Mg contains Tadalafil 20 mg combined with Dapoxetine 60 mg — addressing both ED and premature ejaculation simultaneously in a single tablet. It is the appropriate choice only for men who have both conditions concurrently. For ED alone, a standard Vidalista Tadalafil tablet is the simpler, more targeted option. How long does Super Vidalista 80 Mg last? The two active ingredients have distinctly different durations. Tadalafil's erectile support is active for up to 36 hours — providing a wide window for sexual activity. Dapoxetine's ejaculatory delay effect peaks within 1–2 hours of administration and remains clinically active for approximately 3–4 hours, making it effective for the primary sexual encounter. The full ejaculatory control benefit is most pronounced during this initial 3–4 hour window. Can Super Vidalista 80 Mg be taken with antidepressants? No. Dapoxetine is itself a short-acting SSRI. Combining it with other SSRIs, SNRIs, tricyclic antidepressants, MAOIs, or any other serotonergic medication creates a serious risk of serotonin syndrome — a potentially life-threatening condition characterised by agitation, hyperthermia, rapid heart rate, and muscle rigidity. If you are currently taking any antidepressant or serotonergic medication, inform your prescribing physician before using Super Vidalista 80 Mg. Does Super Vidalista 80 Mg work the first time? Tadalafil's erectile support is typically effective from the first dose. Dapoxetine's ejaculatory delay effect, however, may require 1–2 uses before the full benefit is apparent — as both the pharmacological and psychological aspects of ejaculatory control improve with consistent, confidence-building experience. Men report that performance improves meaningfully after the first 2–3 successful sexual encounters on Super Vidalista. For broader support on optimising sexual performance alongside medication, contact our team — available 24/7. Disclaimer: This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Super Vidalista 80 Mg is a prescription medication. Always consult a licensed healthcare provider before use. Never combine Tadalafil with nitrate medications or Dapoxetine with MAOIs under any circumstances. Ed Care Store does not diagnose or treat any medical condition.