Berberine is a natural plant compound. It has been studied for its ability to activate AMPK, an enzyme that encourages glucose uptake into cells. Berberine HCl (500mg) Milk Thistle (125mg) per capsule Take 1-3 per day Natural Berberine from Berberis Aristata With added natural Milk Thistle to support optimal absorption Suitable for vegans and free from common allergens